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Why Purity Standards Matter: Understanding CoA Reports

A Certificate of Analysis (CoA) is the single most important document accompanying a research peptide. It tells you exactly what is — and is not — in the vial you received.

What a CoA should contain

  • HPLC purity reading — the gold standard (≥99% is the benchmark)
  • Mass spectrometry — confirms molecular identity
  • Appearance and physical description — lyophilised powder, colour, etc.
  • Batch and lot number — traceability
  • Date of analysis — CoAs should be recent

Why ≥99% purity matters

Impurities in research peptides can come from synthesis by-products, incomplete purification, or degradation. Even 1% contamination can introduce variables that skew research outcomes. For reproducible results, ≥99% HPLC purity is the non-negotiable benchmark.

Red flags

  • No CoA provided, or one that is undated
  • Purity below 98%
  • Missing mass spectrometry data
  • Generic or template-looking reports without batch details

At Lumizique, every batch ships with a verified CoA available on request.

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